Victory here would see them rise to sixth – if briefly – while West Brom have humbler goals.
Slaven Bilic’s side, 19th in the standings on six points after their defeat by Newcastle, will struggle to escape the relegation zone even with a win over City. But they’ll be eyeing a huge upset anyway, given 18th Fulham were able to secure a 1-1 draw versus champions Liverpool at the weekend.
Here’s everything you need to know about the top-flight clash:
The game will kick off at 8pm BST at the Etihad Stadium.
The match will air live on Amazon Prime.
Eric Garcia’s muscle issue is set to keep him out a while longer, while Sergio Aguero is a doubt for City after his return last week gave way to an illness-related absence from the Manchester derby.
For West Brom, the injured Conor Townsend and Hal Robson-Kanu will miss out, and Sam Field is unlikely to feature due to his recent injury and positive coronavirus test result. Elsewhere, forward Matheus Pereira is suspended.
Man City: Ederson; Walker, Stones, Dias, Cancelo; Rodri, Gundogan; Sterling, De Bruyne, Torres; Gabriel Jesus
West Brom: Johnstone; Ajayi, Ivanovic, O’Shea; Furlong, Gallagher, Sawyers, Krovinovic, Diangana; Robinson, Grant
Fulham’s spirited showing to gain a point against champions Liverpool will no doubt give West Brom belief that they can get a result here, but it will be a tough task indeed. The safe bet is a comfortable City win. Man City 3-0 West Brom.